University of Minnesota Genomics Center (UMGC) researchers collaborated with more than 20 national and international research institutions to identify a number of genetic markers associated with idiopathic interstitial pneumonia (IIP), a serious and often fatal lung disease with a poorly understood cause. Although there are several variants of IIP, the preponderance of patients in the current study suffered from interstitial pulmonary fibrosis (IPF), the most common and severe IIP.
These genetic locations (loci) led to the identification of neighboring genes proposed to be involved in the cause and/or progression of the disease. Researchers believe these discoveries will move them closer to more effective treatments.
These findings were recently published in Nature Genetics.