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Survival rates in pediatric umbilical cord transplants may indicate a new standard of care

Wednesday, October 29, 2014

A new standard of care for children facing acute myeloid leukemia (AML) may be clear, following a multi-year study published in the latest edition of the New England Journal of Medicine

The research, led by John Wagner, Jr., M.D., director of the Pediatric Blood and Marrow Transplantation program at the University of Minnesota and a researcher in the Masonic Cancer Center, University of Minnesota, compared outcomes in children with acute leukemia and myelodysplastic syndrome who received transplants of either one or two units of partially matched cord blood. The study was conducted at multiple sites nationwide, between December 2006 and February 2012. Coordinating the study was the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) in collaboration with the Pediatric Blood and Marrow Transplant Consortium and the Children’s Oncology Group.

While the study found similar survival rates in both arms of the study, survival was overall better than in prior reports.  This could create a new standard of care for pediatric patients for whom there is often an adequate single unit and adults for whom there is the need for a double unit should a single unit with an adequate number of blood forming stem cells may not exist.

New grant promotes professional development of underrepresented minorities in biomedical research

Friday, October 24, 2014

The University of Minnesota  Program in Health Disparities Research will share an award of $19.2 million from the National Institutes of Health (NIH) to lead professional development activities of underrepresented communities in health science research. The funding will provide intensive grant writing workshops and professional development activities, especially for junior investigators and post-doctoral fellows pursuing biomedical, biobehavioral, clinical and social science research careers. 

University of Minnesota study finds maternal diagnoses doesn’t explain variation in cesarean rates across US hospitals

Tuesday, October 21, 2014

In 2011, cesarean delivery was the most common inpatient surgery in the U.S., making up 32.8 percent of all deliveries and more than 1.3 million births. But while cesarean delivery is common, cesarean rates vary 10-fold across hospitals in the U.S. The reasons for the variability are not well understood.

 

In a new study published today in PLOS Medicine, Katy Kozhimannil, Ph.D., lead author and assistant professor in the School of Public Health at the University of Minnesota and her colleagues at the Harvard School of Public Health, analyzed data from 2009-2010. They looked at more than 1.4 million births in more than 1,300 hospitals, across 46 states, and adjusted rates for maternal diagnoses, socio-demographics and hospital characteristics including size, location and teaching status.

UMN Children’s Hospital Renamed in Honor of Single Largest Donor to the University

Tuesday, October 14, 2014

The University of Minnesota announced today that following a new gift of $25 million dollars from the Minnesota Masonic Charities and in recognition of the legacy of support provided by the Masons to the University of Minnesota, it is renaming the children's hospital to University of Minnesota Masonic Children's Hospital.