Blood and marrow transplantation
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At the University of Minnesota, our pediatric blood and marrow transplant (BMT) program has a legacy of changing perspectives around what is medically possible for children battling some the world’s most complex, life-threatening diseases.
In 1968, University of Minnesota physicians completed the world’s first successful bone marrow transplant. Since then, other “world’s firsts” have followed, including:
- The first transplant to treat a patient with lymphoma (1975)
- The first transplant to treat an inherited metabolic disease (1982)
- The first double umbilical cord blood transplant (1999)
- The first umbilical cord blood transplant performed using pre-implantation genetic testing to ensure a perfect tissue match (2000)
- The first reported success in using Natural Killer (NK) cells to successfully treat advanced myelogenous leukemia.
In 2013, our physicians attempted to cure a pediatric patient of HIV and acute lymphoblastic leukemia via a cord blood transplant containing a variant of the cell surface protein CCR5 – known as CCR5Δ32 - that prevents most strains of the HIV virus from entering a patient’s T cells.
Thanks to such innovation, our BMT program is known as one of the oldest, largest, and most respected pediatric blood and marrow transplant research programs in the world.