John E. Wagner, Jr., MD

Photo of John E. Wagner, Jr., MD

Professor, Department of Pediatrics
Director, Blood and Marrow Transplantation
Department of Pediatrics, Scientific Director of Clinical Research, Stem Cell Institute
Co-Director, Center for Translational Medicine
Children’s Cancer Research Fund/Hageboeck Family Endowed Chair in Pediatric Oncology
McKnight Presidential Chair in Childhood Cancer Research

John E. Wagner, Jr., MD, is at the forefront of blood and marrow transplantation. He specializes in research and treatment of children with cancer. Dr. Wagner has led the University of Minnesota’s Cord Blood Transplantation Program in the treatment of adults and children and is responsible for its international prominence, having first pioneered its use in 1990 in leukemia. Wagner also specializes in Fanconi anemia and the use of stem cells in severe forms of a rare skin disease called epidermolysis bullosa, or EB. Recently, Wagner has begun research on the development of novel stem cell and immune-based therapies derived from cord blood, including the isolation and expansion of hematopoietic stem cells to reduce the time of blood and marrow recovery, regulatory T cells to control graft-versus-host disease (GVHD) and thymic progenitor cells to enhance immune recovery and reduce the risk of relapse and infections after transplantation. Wagner is the co-leader of the Masonic Cancer Center’s Transplant Biology and Therapy Research Program.